B12, folate, B6 and energy claims

B Vitamins

B vitamins correct deficiency well and do very little beyond it. Here is where supplementation is genuinely justified and where the 'energy' marketing outruns the data.

What the evidence says

  • B12 supplementation is well supported for vegans, older adults and metformin users.
  • Folate matters most before and during pregnancy.
  • In people who are not deficient, high-dose B complexes do not reliably improve energy or mood.

Supplements in this topic

Vitamins

Multivitamin

Limited evidence

For most well-nourished adults, multivitamins do not reduce mortality or prevent chronic disease. May help fill gaps in restricted diets.

Verdict: Insurance policy, not a longevity pill.

310 studies reviewed
Can lead to excessive intake of some fat-soluble vitamins

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